microRNAs: From Basic Science to Disease Biology
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Book Summary Information
Foreword: Sidney AltmanForeword: Victor R. Ambros
Editor: Krishnarao Appasani
Edition: Hardcover
Audio: English (Original Language); English (Unknown); English (Published)
Published: 2008-01-21
ISBN: 0521865980
Number of pages: 560
Publisher: Cambridge University Press
Summary of microRNAs: From Basic Science to Disease Biology
MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development.Forewords by:
Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989
and
Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs
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